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A Phase 1 Study of the SHP2 Inhibitor BBP-398 (Formerly Known as IACS-15509) in Combination With the KRAS-G12C Inhibitor Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C Mutation

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Trial Profile

A Phase 1 Study of the SHP2 Inhibitor BBP-398 (Formerly Known as IACS-15509) in Combination With the KRAS-G12C Inhibitor Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C Mutation

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 17 Dec 2024

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At a glance

  • Drugs BBP 398 (Primary) ; Sotorasib (Primary)
  • Indications Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms Agronaut
  • Sponsors Navire

Most Recent Events

  • 12 Dec 2024 Status changed from recruiting to discontinued.
  • 03 Aug 2022 New trial record

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