Trial Profile

A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512, a Cold Thermoreceptor Modulator, for the Treatment of Dry Eye Disease (COMET-4)

Status: Completed

Phase of Trial: Phase III

Latest Information Update: 28 Apr 2025

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At a glance

Drugs Acoltremon (Primary)
Indications Dry eyes
Focus Adverse reactions; Registrational; Therapeutic Use
Acronyms COMET-4
Sponsors Aerie Pharmaceuticals; Alcon

Most Recent Events

17 Apr 2025 According to an Alcon media release, the data from this study will be presented at the 2025 American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting, April 25-28, in Los Angeles.
23 Apr 2024 Status changed from active, no longer recruiting to completed.
09 Mar 2023 Status changed from recruiting to active, no longer recruiting.

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