HEAT-AML (Hydroxyurea-Enhanced Ara-C Treatment of Adult Acute Myeloid Leukaemia): A phase I/II multicenter study to assess the tolerability and efficacy of the addition of hydroxyurea to standard ara-C and daunorubicin-based therapy for adults (age ≥ 18 years of age) with newly diagnosed acute myeloid leukaemia (AML)
Latest Information Update: 21 Mar 2024
At a glance
- Drugs Hydroxycarbamide (Primary) ; Cytarabine; Daunorubicin; Midostaurin
- Indications Acute myeloid leukaemia
- Focus Therapeutic Use
- Acronyms HEAT-AML
- 01 Dec 2022 Results (n=9) reporting PK, safety and efficacy data from phase 1 portion of this trial published in the Journal of Internal Medicine
- 05 Aug 2022 New trial record
- 17 Jun 2022 Results of the first 9 patients in the run-in phase 1 part of the study presented at the 27th Congress of the European Haematology Association