Pan tumour trial of COX-inhibitor and immune checkpoint blockade
Latest Information Update: 17 May 2024
At a glance
- Drugs Atezolizumab (Primary) ; Celecoxib (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
- Indications Adenocarcinoma; Advanced breast cancer; Carcinoma; HER2 negative breast cancer; Male breast cancer; Non-small cell lung cancer; Renal cell carcinoma; Triple negative breast cancer
- Focus Therapeutic Use
- Acronyms LION
Most Recent Events
- 14 May 2024 Planned End Date changed from 3 Jun 2026 to 7 May 2027.
- 26 Apr 2023 Status changed from not yet recruiting to recruiting.
- 14 Oct 2022 The recruitment start date was changed from 31/10/2022 to 31/01/2023.The recruitment end date was changed from 10/12/2023 to 01/01/2025.