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A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of TLC-2716 in Healthy Subjects

Trial Profile

A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of TLC-2716 in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 22 May 2024

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At a glance

  • Drugs TLC-2716 (Primary)
  • Indications Dyslipidaemias; Hypercholesterolaemia; Hypertriglyceridaemia; Non-alcoholic steatohepatitis
  • Focus Adverse reactions; First in man
  • Sponsors The Liver Company

Most Recent Events

  • 17 May 2024 Status changed from active, no longer recruiting to completed.
  • 13 Nov 2023 Results (n=100) assessing Safety, Pharmacokinetics, and Lipid Lowering Effects of the Oral, Liver-Targeted Liver X Receptor (LXR) Inverse Agonist TLC-2716 in Healthy Volunteers presented at the American Heart Association Scientific Sessions 2023
  • 06 Nov 2023 Results presented in the OrsoBio Media Release

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