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Neoadjuvant and Adjuvant Olaparib Plus Pembrolizumab Following Platinum Based Chemotherapy Plus Pembrolizumab for Germline BRCA Mutated Triple Negative Breast Cancer (WJOG14020B/OPERETTA)

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Trial Profile

Neoadjuvant and Adjuvant Olaparib Plus Pembrolizumab Following Platinum Based Chemotherapy Plus Pembrolizumab for Germline BRCA Mutated Triple Negative Breast Cancer (WJOG14020B/OPERETTA)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 24 Mar 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Olaparib (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
  • Indications Advanced breast cancer; Early breast cancer; Male breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use
  • Acronyms WJOG14020B

    • Most Recent Events

    • 20 Mar 2025 Planned End Date changed from 30 Sep 2027 to 30 Sep 2028.
    • 20 Mar 2025 Planned primary completion date changed from 30 Sep 2025 to 30 Jun 2028.
    • 09 Feb 2024 Planned initiation date changed from 1 Oct 2022 to 29 Feb 2024.

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