A Phase 1/2a Open-Label, Dose Escalation and Expansion Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Mirdametinib in Combination With BGB-3245 in Patients With Advanced Solid Tumors
Latest Information Update: 24 Feb 2025
At a glance
- Drugs Brimarafenib (Primary) ; Mirdametinib (Primary)
- Indications Solid tumours
- Focus Adverse reactions; Therapeutic Use
- Sponsors SpringWorks Therapeutics
Most Recent Events
- 17 Feb 2025 Status changed from active, no longer recruiting to discontinued.
- 26 Oct 2024 Status changed from recruiting to active, no longer recruiting.
- 01 Feb 2023 According to SpringWorks media release, the first patient was dosed in a Phase 1/2a combination study of BGB-3245 and mirdametinib,