A Phase II, Multicentre, Open-Label Study to Assess the Efficacy and Safety of Olaparib Monotherapy and Olaparib Plus Durvalumab Combination as Neoadjuvant Therapy in Patients With BRCA Mutations and Early Stage HER2-Negative Breast Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 06 Mar 2025

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At a glance

Drugs Durvalumab (Primary) ; Olaparib (Primary)
Indications Early breast cancer; HER2 negative breast cancer; Male breast cancer
Focus Therapeutic Use
Acronyms OlympiaN
Sponsors AstraZeneca; AstraZeneca AB

Most Recent Events

30 Oct 2024 Planned primary completion date changed from 2 May 2024 to 20 Nov 2024.
08 May 2024 Planned End Date changed from 7 Dec 2026 to 31 Dec 2026.
08 May 2024 Planned primary completion date changed from 8 Apr 2024 to 2 May 2024.

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