Trial Profile

A Phase 1b, Double-Blind, Placebo-Controlled, Multiple Ascending Dose and an Open-Label Fixed-Dose Study in Patients With Autosomal Dominant Polycystic Kidney Disease to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RGLS8429

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 08 May 2025

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At a glance

30 Apr 2025 Status changed from active, no longer recruiting to completed.
27 Mar 2025 According to a Regulus Therapeutics media release, company announced positive topline results from all patients in the fourth cohort in its Phase 1b MAD study of farabursen for the treatment of ADPKD.
27 Mar 2025 Results published in the Regulus Therapeutics media release

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