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An Open-Label, Single-Sequence Study to Assess the Effect of Multiple Doses of Zibotentan on the Pharmacokinetics of Single Doses of Combined Oral Ethinyl Estradiol and Levonorgestrel in Healthy Female Participants of Non-Child-Bearing Potential

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Trial Profile

An Open-Label, Single-Sequence Study to Assess the Effect of Multiple Doses of Zibotentan on the Pharmacokinetics of Single Doses of Combined Oral Ethinyl Estradiol and Levonorgestrel in Healthy Female Participants of Non-Child-Bearing Potential

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Feb 2023

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At a glance

  • Drugs Ethinylestradiol/levonorgestrel (Primary) ; Zibotentan (Primary)
  • Indications Liver cirrhosis; Liver failure; Renal failure
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

Most Recent Events

  • 08 Feb 2023 Status changed from active, no longer recruiting to completed.
  • 12 Dec 2022 Status changed from recruiting to active, no longer recruiting.
  • 07 Oct 2022 Planned number of patients changed from 42 to 24.

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