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An Open-label, Multi-center Phase Ib/III Study Evaluating the Efficacy and Safety of IBI351 in Combination With Sintilimab ± Chemotherapy in Advanced Non-squamous Non-small Cell Lung Cancer Subjects With KRAS G12C Mutation

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Trial Profile

An Open-label, Multi-center Phase Ib/III Study Evaluating the Efficacy and Safety of IBI351 in Combination With Sintilimab ± Chemotherapy in Advanced Non-squamous Non-small Cell Lung Cancer Subjects With KRAS G12C Mutation

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 29 Jan 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Fulzerasib (Primary) ; Pemetrexed (Primary) ; Sintilimab (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Innovent Biologics

    • Most Recent Events

    • 27 Jan 2025 Planned primary completion date changed from 12 May 2024 to 31 May 2025.
    • 25 May 2023 the experimental arm- IBI351 in combination with Cetuximab has been updated and cetuximab has been removed from the study regimen.
    • 25 May 2023 Planned primary completion date changed from 12 May 2023 to 12 May 2024.

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