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A Phase 2a Randomized, Observer-blind, Placebo-controlled, Dosage Optimization, Multi-center Clinical Trial to Evaluate the Safety and Immunogenicity of IVX-A12, a Respiratory Syncytial Virus and Human Metapneumovirus Bivalent Combination Virus-like Particle Protein Subunit Vaccine, in Adults 60 to 85 Years of Age

Trial Profile

A Phase 2a Randomized, Observer-blind, Placebo-controlled, Dosage Optimization, Multi-center Clinical Trial to Evaluate the Safety and Immunogenicity of IVX-A12, a Respiratory Syncytial Virus and Human Metapneumovirus Bivalent Combination Virus-like Particle Protein Subunit Vaccine, in Adults 60 to 85 Years of Age

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 26 May 2025

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At a glance

  • Drugs IVX-A12 (Primary) ; MF 59
  • Indications Metapneumovirus infections; Respiratory syncytial virus infections
  • Focus Adverse reactions; Pharmacodynamics; Proof of concept
  • Sponsors Icosavax

Most Recent Events

  • 16 Oct 2024 According to AstraZeneca media release, data from this trial will be presented at IDWeek 2024
  • 10 Apr 2024 Planned End Date changed from 30 Sep 2024 to 30 Sep 2025.
  • 10 Apr 2024 Planned primary completion date changed from 10 May 2024 to 5 Jul 2025.

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