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A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of Ensifentrine Over 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Trial Profile

A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of Ensifentrine Over 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2025

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At a glance

  • Drugs Ensifentrine (Primary)
  • Indications Chronic obstructive pulmonary disease
  • Focus Pharmacokinetics; Registrational
  • Acronyms ENHANCE-CHINA
  • Sponsors Nuance Pharma

Most Recent Events

  • 16 Sep 2025 According to a Verona Pharma media release, posters on additional analyses from its Phase 3 ENHANCE studies will be presented at the European Respiratory Society (ERS) International Congress 2025. The abstracts are available to conference participants on the ERS website and will be published in an upcoming issue of the peer reviewed publication, European Respiratory Journal.
  • 16 Jun 2025 According to a Verona Pharma media release, company plan to submit a New Drug Application to the China NMPA in the second half of 2025.
  • 16 Jun 2025 Primary endpoint(Average forced expiratory volume in 1 second (FEV1) area under the curve (AUC)0-12h) has been met.

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