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A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of Ensifentrine Over 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Trial Profile

A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of Ensifentrine Over 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 Jun 2025

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At a glance

  • Drugs Ensifentrine (Primary)
  • Indications Chronic obstructive pulmonary disease
  • Focus Pharmacokinetics; Registrational
  • Acronyms ENHANCE-CHINA
  • Sponsors Nuance Pharma

Most Recent Events

  • 16 Jun 2025 According to a Verona Pharma media release, company plan to submit a New Drug Application to the China NMPA in the second half of 2025.
  • 16 Jun 2025 Primary endpoint(Average forced expiratory volume in 1 second (FEV1) area under the curve (AUC)0-12h) has been met.
  • 16 Jun 2025 Results presented in the Verona Pharma media release.

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