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Phase 2 Study with Safety Run-in of PD-1 Inhibitor and IgG4 SIRPα-Fc Fusion Protein (TTI-622) in Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)

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Trial Profile

Phase 2 Study with Safety Run-in of PD-1 Inhibitor and IgG4 SIRPα-Fc Fusion Protein (TTI-622) in Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Sep 2024

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At a glance

  • Drugs Maplirpacept (Primary) ; Ontorpacept (Primary) ; Pembrolizumab (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; T-cell lymphoma
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 13 Sep 2024 Planned number of patients changed from 62 to 41.
    • 20 Apr 2023 Status changed from not yet recruiting to recruiting.
    • 01 Feb 2023 Planned initiation date changed from 15 Jan 2023 to 15 Mar 2023.

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