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A Randomized, Observer-Blinded, Vehicle-Controlled Study on the Safety and Efficacy of Twice Daily Application of Ruboxistaurin (DBI-102) Gel Vs.Vehicle Gel Vs. Hydroquinone Cream on Sun-Exposed and Sun-Protected Skin of Adults

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Trial Profile

A Randomized, Observer-Blinded, Vehicle-Controlled Study on the Safety and Efficacy of Twice Daily Application of Ruboxistaurin (DBI-102) Gel Vs.Vehicle Gel Vs. Hydroquinone Cream on Sun-Exposed and Sun-Protected Skin of Adults

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 08 Nov 2024

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At a glance

  • Drugs Ruboxistaurin (Primary) ; Hydroquinone
  • Indications Hyperpigmentation
  • Focus Therapeutic Use
  • Sponsors DermBiont

    • Most Recent Events

    • 22 Feb 2024 According to a DermBiont media release, The CT-214 trial follows positive results of this completed Phase 2a study treating solar lentigos and photoinduced hyperpigmentation, demonstrating comparable efficacy to hydroquinone with superior tolerability and safety given SM-030s targeted mechanism of action and increasing concerns over hydroquinones long-term safety and toxicity.
    • 23 Oct 2023 Status changed from recruiting to completed.
    • 26 Aug 2022 New trial record

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