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A First In Human Multicenter, Open-Label Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-319 in B-cell Malignancies

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Trial Profile

A First In Human Multicenter, Open-Label Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-319 in B-cell Malignancies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 09 Jun 2025

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At a glance

  • Drugs ABBV-319 (Primary)
  • Indications Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors AbbVie

Most Recent Events

  • 05 Feb 2025 Planned number of patients changed from 114 to 154.
  • 05 Feb 2025 Planned End Date changed from 7 Feb 2027 to 1 Feb 2027.
  • 05 Feb 2025 Planned primary completion date changed from 7 Feb 2027 to 1 Feb 2027.

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