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A Phase 1, Open-label, Multicenter Study of the Safety, Pharmacokinetics, and Pharmacodynamics of MK-4464 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced/Metastatic Solid Tumors

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Trial Profile

A Phase 1, Open-label, Multicenter Study of the Safety, Pharmacokinetics, and Pharmacodynamics of MK-4464 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced/Metastatic Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 13 Jun 2025

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At a glance

  • Drugs MK-4464 (Primary) ; Pembrolizumab (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions
  • Sponsors Merck Sharp & Dohme Corp.

Most Recent Events

  • 09 Jun 2025 Planned End Date changed from 17 Jul 2026 to 31 Mar 2026.
  • 09 Jun 2025 Planned primary completion date changed from 17 Jul 2026 to 31 Mar 2026.
  • 14 Aug 2024 Planned End Date changed from 26 Oct 2027 to 17 Jul 2026.

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