Trial Profile

A Single-dose, Open-label, Single Arm Study to Investigate PK of Xevinapant (Debio 1143) and Its Metabolite, D-1143-MET1 in Healthy East Asian Participants

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 24 Sep 2025

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At a glance

Drugs Xevinapant (Primary)
Indications Adenocarcinoma; Colorectal cancer; Non-small cell lung cancer; Ovarian cancer; Solid tumours; Squamous cell cancer
Focus Pharmacokinetics
Sponsors Merck KGaA

Most Recent Events

26 Apr 2023 Status changed from active, no longer recruiting to completed.
14 Nov 2022 Planned number of patients changed from 20 to 24.
14 Nov 2022 Status changed from recruiting to active, no longer recruiting.

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