Trial Profile

A Phase 3, Two-Stage, Randomized, Multicenter, Open-Label Study Comparing Mezigdomide (CC-92480), Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Subjects With Relapsed or Refractory Multiple Myeloma (RRMM): SUCCESSOR-1

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 19 Jun 2025

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At a glance

Drugs Bortezomib (Primary) ; Dexamethasone (Primary) ; Dexamethasone (Primary) ; Mezigdomide (Primary) ; Pomalidomide (Primary)
Indications Multiple myeloma
Focus Registrational; Therapeutic Use
Acronyms Successor-1
Sponsors Bristol-Myers Squibb; Celgene Corporation

12 Jun 2025 According to a Bristol Myers Squibb media release, results form this trial are expected in the 2026.
25 Oct 2023 Planned number of patients changed from 760 to 810.
13 Feb 2023 Planned End Date changed from 13 Dec 2033 to 30 Nov 2033.

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