Trial Profile

Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 22 Apr 2026

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At a glance

Drugs Blinatumomab (Primary) ; Methotrexate
Indications Neurotoxicity syndrome; Precursor B-cell lymphoblastic leukaemia-lymphoma
Focus Adverse reactions

Most Recent Events

07 Apr 2026 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.
07 Apr 2026 Planned primary completion date changed from 1 Nov 2025 to 1 Nov 2026.
13 Dec 2024 Planned End Date changed from 1 Aug 2025 to 1 Dec 2025.

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