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Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IA-14069 in Healthy Subjects, With an Extension to Explore Any Drug-Drug Interaction Potential With Methotrexate (Part 1), and in Patients With Rheumatoid Arthritis, With Preliminary Assessment of Efficacy in Patients (Part 2)

Trial Profile

Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IA-14069 in Healthy Subjects, With an Extension to Explore Any Drug-Drug Interaction Potential With Methotrexate (Part 1), and in Patients With Rheumatoid Arthritis, With Preliminary Assessment of Efficacy in Patients (Part 2)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 27 May 2025

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At a glance

  • Drugs IA-14069 (Primary) ; Methotrexate (Primary)
  • Indications Rheumatoid arthritis
  • Focus Adverse reactions
  • Sponsors iLab

Most Recent Events

  • 20 May 2025 Planned End Date changed from 1 Dec 2024 to 1 Feb 2026.
  • 20 May 2025 Planned primary completion date changed from 1 Sep 2024 to 1 Nov 2025.
  • 11 Oct 2023 Planned End Date changed from 1 Nov 2023 to 1 Dec 2024.

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