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RCT of Neurocognitive and Neuroimaging Biomarkers: Predicting Progression Towards Dementia in Patients With Treatment-resistant Late-life Depression (OPTIMUM-Neuro RCT)

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Trial Profile

RCT of Neurocognitive and Neuroimaging Biomarkers: Predicting Progression Towards Dementia in Patients With Treatment-resistant Late-life Depression (OPTIMUM-Neuro RCT)

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 27 Nov 2024

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At a glance

  • Drugs Aripiprazole (Primary) ; Bupropion (Primary) ; Lithium (Primary) ; Nortriptyline (Primary)
  • Indications Major depressive disorder
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms OPT-Neuro RCT; OPTIMUM-Neuro RCT

    • Most Recent Events

    • 25 Nov 2024 Status changed from active, no longer recruiting to completed.
    • 16 Oct 2023 Planned primary completion date changed from 31 Jan 2024 to 30 Apr 2024.
    • 14 Sep 2022 New trial record

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