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A Phase IB and Randomized Phase II Trial of Megestrol Acetate With or Without Ipatasertib in Recurrent or Metastatic Endometrioid Endometrial Cancer

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A Phase IB and Randomized Phase II Trial of Megestrol Acetate With or Without Ipatasertib in Recurrent or Metastatic Endometrioid Endometrial Cancer

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 12 Mar 2025

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At a glance

  • Drugs Ipatasertib (Primary) ; Megestrol (Primary)
  • Indications Adenocarcinoma; Endometrial cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 27 Feb 2024 Status changed from suspended to recruiting.
    • 15 Feb 2024 The protocol has been amended in Megestrol acetate dose frequency changes from days 1 to 28 and ipatasertib PO QD dose changes from days 1 to21 of every cycle.
    • 16 Nov 2023 Status changed from recruiting to suspended for the review of safety data of Phase IB.

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