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A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed Non-alcoholic Steatohepatitis (NASH)

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Trial Profile

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed Non-alcoholic Steatohepatitis (NASH)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 15 Sep 2025

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At a glance

  • Drugs DA 1241 (Primary) ; Sitagliptin
  • Indications Non-alcoholic steatohepatitis; Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Sponsors MetaVia; NeuroBo Pharmaceuticals

Most Recent Events

  • 04 Aug 2025 According to a Metavia media release, following positive results from this trial the company formed a research collaboration with Syntekabio,to identify additional disease targets and optimize the therapeutic profile of DA-1241.
  • 07 May 2025 According to a Metavia media release, data from this study findings from this study will be reviewed at end of Phase 2 meeting with the U.S. Food and Drug Administration (FDA) in the first half of 2025."
  • 07 May 2025 According to a Metavia media release, data from this study presented at the European Association for the Study of the Liver (EASL) Congress 2025, taking place May 7-10, 2025, in Amsterdam, the Netherlands.

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