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A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed Non-alcoholic Steatohepatitis (NASH)

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Trial Profile

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed Non-alcoholic Steatohepatitis (NASH)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Jan 2025

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At a glance

  • Drugs DA 1241 (Primary) ; Sitagliptin
  • Indications Non-alcoholic steatohepatitis; Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Sponsors MetaVia; NeuroBo Pharmaceuticals

    • Most Recent Events

    • 10 Jan 2025 According to a Metavia media release, the company is holding an Advisory Committee meeting today, at the 9th Annual MASH-TAG 2025 Conference, to discuss the previously announced positive top-line 16-week results from the two-part Phase 2a clinical trial of DA-1241
    • 19 Dec 2024 According to a Metavia media release, the company announced release of positive top-line 16-week results from this trial MASH-TAG Conference which is taking place January 9-11 at the Chateaux Deer Valley in Park City, Utah.
    • 18 Dec 2024 Primary endpoint has not been met (Part1 & Part 2: Change alanine transaminase (ALT) levels) , according to a NeuroBo Pharmaceuticals media release

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