Trial Profile

Persistence of binding and neutralizing antibodies against SARS-CoV2 strains at 6 months or more after a third dose with recombinant COVID-19 vaccine (AstraZeneca/Fiocruz), mRNA COVID-19 vaccine (Comirnaty, Pfizer/Wyeth), recombinant COVID-19 vaccine (Janssen) or adsorbed inactivated COVID-19 vaccine Coronavac (Sinovac/Butantan) in subjects primed with two Sinovac/Butantan doses – extension of study RHH_001; and assessment of safety and immunogenicity of 4th dose with recombinant COVID-19 vaccine (AstraZeneca/Fiocruz) or mRNA covid-19 vaccine (Comirnaty, Pfizer/Wyeth).

Status: Completed

Phase of Trial: Phase IV

Latest Information Update: 07 Jul 2023

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At a glance

Drugs AZD 1222 (Primary) ; Tozinameran (Primary) ; SARS-COV-2 vaccine-inactivated-Sinovac-Biotech
Indications COVID 2019 infections
Focus Pharmacodynamics

19 Sep 2022 Recruitment completion is expected on 04.09.2022 according to ISRCTN Clinical Trials Registry record.
19 Sep 2022 New trial record

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