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A Randomized, 52-week Treatment Double-blind, Placebo-controlled Efficacy and Safety Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusitis (AFRS) on a Background Therapy With Intranasal Corticosteroid Spray

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Trial Profile

A Randomized, 52-week Treatment Double-blind, Placebo-controlled Efficacy and Safety Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusitis (AFRS) on a Background Therapy With Intranasal Corticosteroid Spray

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 16 May 2025

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At a glance

  • Drugs Dupilumab (Primary)
  • Indications Nasal polyps; Rhinosinusitis
  • Focus Therapeutic Use
  • Acronyms ADAPT

Most Recent Events

  • 18 Jul 2024 Status changed from recruiting to discontinued.
  • 11 Oct 2023 Status changed from not yet recruiting to recruiting.
  • 05 Jul 2023 Planned initiation date changed from 1 Jun 2023 to 1 Aug 2023.

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