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A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY AND TOLERABILITY OF PONSEGROMAB IN PATIENTS WITH CANCER, CACHEXIA, AND ELEVATED CONCENTRATIONS OF GDF-15, FOLLOWED BY AN OPTIONAL OPEN-LABEL TREATMENT PERIOD (PROACC -1)

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A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY AND TOLERABILITY OF PONSEGROMAB IN PATIENTS WITH CANCER, CACHEXIA, AND ELEVATED CONCENTRATIONS OF GDF-15, FOLLOWED BY AN OPTIONAL OPEN-LABEL TREATMENT PERIOD (PROACC -1)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Feb 2025

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At a glance

  • Drugs Ponsegromab (Primary)
  • Indications Cachexia
  • Focus Therapeutic Use
  • Acronyms PROACC -1
  • Sponsors Pfizer

    • Most Recent Events

    • 31 Jan 2025 Planned End Date changed from 30 Apr 2025 to 21 Apr 2025.
    • 14 Sep 2024 According to a Pfizer media release, results from this trial published in The New England Journal of Medicine (NEJM).
    • 14 Sep 2024 According to a Pfizer media release, results from this trial will be presented today as a late-breaking Proffered Paper Presentation (LBA82) at the European Society for Medical Oncology (ESMO) 2024 Congress. Jeffrey Crawford, M.D is the principal investigator of this trial.

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