A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF)
Latest Information Update: 19 Mar 2025
At a glance
- Drugs Doravirine/islatravir (Primary) ; Bictegravir/emtricitabine/tenofovir alafenamide
- Indications HIV-1 infections
- Focus Adverse reactions; Registrational; Therapeutic Use
- Sponsors Merck & Co; Merck Sharp & Dohme
- 12 Mar 2025 According to Merck & Co media release, data from this trial will be presented at the 32nd Conference on Retroviruses and Opportunistic Infections (CROI)
- 12 Mar 2025 Results presented in the Merck & Co Media Release
- 19 Dec 2024 According to Merck Media Release, Primary endpoint (Percentage of participants with HIV-1 RNA 50 copies/mL at Week 48 [ Time Frame: Week 48 ])has been met.