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A Randomized, Double-blind, Multicenter, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

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Trial Profile

A Randomized, Double-blind, Multicenter, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 12 Mar 2025

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At a glance

  • Drugs Aticaprant (Primary)
  • Indications Major depressive disorder
  • Focus Registrational; Therapeutic Use
  • Acronyms VENTURA-2
  • Sponsors Janssen Research & Development

Most Recent Events

  • 10 Mar 2025 Status changed from recruiting to completed.
  • 22 Jan 2025 Planned End Date changed from 9 Jul 2025 to 10 Jul 2025.
  • 20 Dec 2024 Planned End Date changed from 13 Dec 2024 to 9 Jul 2025.

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