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Phase 1 Study to Determine the Safety and Efficacy of Onvansertib, a Novel, Oral, PLK1 Inhibitor in Patients with Proliferative Chronic Myelomonocytic Leukemia (CMML) and Myelodysplastic Syndrome/MPN Overlap Neoplasms Relapsed/Refractory or Intolerant to Available Therapies

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Trial Profile

Phase 1 Study to Determine the Safety and Efficacy of Onvansertib, a Novel, Oral, PLK1 Inhibitor in Patients with Proliferative Chronic Myelomonocytic Leukemia (CMML) and Myelodysplastic Syndrome/MPN Overlap Neoplasms Relapsed/Refractory or Intolerant to Available Therapies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 21 Feb 2025

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At a glance

  • Drugs Onvansertib (Primary)
  • Indications Chronic myelomonocytic leukaemia
  • Focus Adverse reactions

    • Most Recent Events

    • 14 Feb 2025 Planned End Date changed from 8 Mar 2027 to 1 Dec 2027.
    • 14 Feb 2025 Planned primary completion date changed from 29 Dec 2026 to 1 Jun 2027.
    • 26 Feb 2024 Planned End Date changed from 30 Dec 2026 to 8 Mar 2027.

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