Trial Profile

TCRαβ+ T-cell/CD19+ B-cell Depleted Hematopoietic Grafts and a Reduced Intensity Preparative Conditioning Regimen Containing JSP191 to Achieve Engraftment and Blood Reconstitution in Patients With Fanconi Anemia

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 04 Feb 2026

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At a glance

Drugs Briquilimab (Primary) ; Antithymocyte globulin; Cyclophosphamide; Fludarabine; Rituximab
Indications Fanconi's anaemia
Focus Adverse reactions; Therapeutic Use

04 Feb 2026 Planned number of patients changed from 12 to 18.
27 Jan 2026 Planned End Date changed from 1 Dec 2027 to 1 Dec 2028.
27 Jan 2026 Planned primary completion date changed from 1 Dec 2025 to 1 Dec 2027.

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