A ComboMATCH Treatment Trial EAY191-N2: Phase 2 Trial of Fulvestrant and Binimetinib in Patients With Hormone Receptor-Positive Metastatic Breast Cancer With a Frameshift or Nonsense Mutation or Genomic Deletion in NF1
Latest Information Update: 21 Apr 2025
At a glance
- Drugs Binimetinib (Primary) ; Fulvestrant (Primary)
- Indications Advanced breast cancer; Carcinoma; Male breast cancer
- Focus Therapeutic Use
- Acronyms ComboMATCH
Most Recent Events
- 16 Apr 2025 Status changed from active, no longer recruiting to discontinued due to slow accrual
- 11 Feb 2025 Status changed from recruiting to active, no longer recruiting.
- 28 Aug 2024 Planned initiation date (estimated date for recruitment of the first subject) changed from 27 Aug 2024 to 25 Nov 2024.