A Randomized Phase 3 Study of Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in Subjects With No Prior Therapy for Advanced or Metastatic PD-L1 TPS <50% Non-squamous Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-Lung07)
Latest Information Update: 02 Jul 2026
At a glance
- Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Datopotamab deruxtecan (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
- Indications Non-small cell lung cancer
- Focus Registrational; Therapeutic Use
- Acronyms TROPION-Lung07
- Sponsors Daiichi Sankyo Inc
Most Recent Events
- 23 Jun 2026 Planned End Date changed from 1 Aug 2027 to 11 May 2031.
- 12 Jan 2026 Status changed from recruiting to active, no longer recruiting.
- 07 Nov 2024 Planned number of patients changed from 975 to 1170.