A Phase I Dose Escalation Study of Ascending Single and Multiple Doses of the MEK Inhibitor Zapnometinib in Healthy Subjects to Evaluate the Safety & Tolerability Compared to Placebo, Additionally Evaluating Pharmacokinetics and Pharmacodynamics of Target Engagement, as Well as Investigating Possible FDI and DDI
Latest Information Update: 03 Aug 2023
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At a glance
- Drugs Zapnometinib (Primary) ; Celecoxib; Repaglinide
- Indications COVID 2019 infections; Hantavirus infections; Influenza virus infections
- Focus Adverse reactions
- Sponsors Atriva Therapeutics
- 28 Jul 2023 Status changed from recruiting to completed.
- 06 Feb 2023 Planned number of patients changed from 109 to 96.
- 06 Feb 2023 Planned End Date changed from 1 Oct 2023 to 1 Jul 2023.