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Phase II Trial of BXCL701 and Pembrolizumab in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Trial Profile

Phase II Trial of BXCL701 and Pembrolizumab in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 26 Mar 2025

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At a glance

  • Drugs Pembrolizumab (Primary) ; Talabostat (Primary)
  • Indications Adenocarcinoma; Pancreatic ductal carcinoma
  • Focus Proof of concept; Therapeutic Use
  • Acronyms EXPEL PANC

Most Recent Events

  • 04 Jun 2024 Results (n=6) assessing safety and efficacy of BXCL701 and pembrolizumab in patients with metastatic pancreatic ductal adenocarcinoma presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 24 Apr 2024 According to a BioXcel Therapeutics media release, the company announced that preliminary findings from the Phase 2 investigator-sponsored trial of BXCL701 in combination with KEYTRUDA in previously treated metastatic pancreatic ductal adenocarcinoma (PDAC) has been selected for presentation in a poster session at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting from May 31 to June 4, 2024 in Chicago, IL.
  • 06 Feb 2024 According to a BioXcel Therapeutics media release, the human proof of concept portion of the trial is expected to start in H1 2024.

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