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KRAKEN: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Oral Once-Daily LY3473329 in Adults With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events

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Trial Profile

KRAKEN: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Oral Once-Daily LY3473329 in Adults With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 31 Jan 2025

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At a glance

  • Drugs Muvalaplin (Primary)
  • Indications Hyperlipoproteinaemia
  • Focus Therapeutic Use
  • Acronyms KRAKEN
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 18 Nov 2024 Results assessing the efficacy and tolerability of muvalaplin, presented at the American Heart Association Scientific Sessions 2024.
    • 18 Nov 2024 Primary endpoint (Percent Change from Baseline in Lipoprotein (a) Lp(a)) has been met.
    • 18 Nov 2024 According to an Eli Lilly and Company media release, Phase 2 results were published in the Journal of the American Medical Association (JAMA) and simultaneously presented today at the American Heart Association (AHA) Scientific Sessions 2024

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