Trial Profile

A Randomized, Controlled, Open-label, Multicenter, Inferentially Seamless Phase 2/3 Study of Ibrutinib in Combination With Rituximab Versus Physician's Choice of Lenalidomide Plus Rituximab or Bortezomib Plus Rituximab in Participants With Relapsed or Refractory Mantle Cell Lymphoma

Status: Completed

Phase of Trial: Phase II/III

Latest Information Update: 15 Jan 2025

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At a glance

Drugs Bortezomib (Primary) ; Bortezomib (Primary) ; Ibrutinib (Primary) ; Lenalidomide (Primary) ; Rituximab (Primary)
Indications Mantle-cell lymphoma
Focus Adverse reactions; Therapeutic Use
Acronyms VEGA
Sponsors Janssen Research & Development

11 Oct 2024 Status changed from active, no longer recruiting to completed.
26 Mar 2024 Planned End Date changed from 1 Jul 2033 to 30 Sep 2024.
19 Dec 2023 This trial has been completed in Greece, according to European Clinical Trials Database record.

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