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A Randomized, Double-Blind, Placebo-Controlled Dose Escalation Clinical Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide (iNO) in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis on Long Term Oxygen Therapy (Part 1 and Part 2)

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Dose Escalation Clinical Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide (iNO) in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis on Long Term Oxygen Therapy (Part 1 and Part 2)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Mar 2024

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At a glance

  • Drugs Nitric oxide (Primary)
  • Indications Pulmonary fibrosis; Pulmonary hypertension
  • Focus Therapeutic Use
  • Acronyms iNO-PF
  • Sponsors Bellerophon Therapeutics
  • Most Recent Events

    • 10 Oct 2022 New trial record
    • 15 Jul 2020 According to a Bellerophon Therapeutics media release, the company completed Cohort 2 of this study, which assessed a higher iNO45 (45 mcg/kg IBW/hr) dose.
    • 17 Dec 2019 Top-line results from cohort 2 of the study presented in a Bellerophon Therapeutics media release.

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