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A Randomized, Open Labeled Phase II Pilot Study of Total Neoadjuvant Chemotherapy With FLOT ( FLOT-TNT) VS Standard Perioperative FLOT ( FLOTPOP) in Patients With Gastric or GEJ Cancer, and Assessment of CTDNA as Correlative Biological Response

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A Randomized, Open Labeled Phase II Pilot Study of Total Neoadjuvant Chemotherapy With FLOT ( FLOT-TNT) VS Standard Perioperative FLOT ( FLOTPOP) in Patients With Gastric or GEJ Cancer, and Assessment of CTDNA as Correlative Biological Response

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 04 Apr 2025

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At a glance

  • Drugs Docetaxel (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Oxaliplatin (Primary) ; Granulocyte colony-stimulating factor receptor agonists
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Pharmacogenomic; Therapeutic Use
  • Acronyms TOGAR

    • Most Recent Events

    • 01 Apr 2025 Status changed from recruiting to discontinued.
    • 14 Mar 2024 Status changed from not yet recruiting to recruiting.
    • 11 Jan 2024 Planned initiation date changed from 1 Dec 2023 to 31 Mar 2024.

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