Neoadjuvant Treatment With mFOLFOXIRI Plus Cadonilimab (AK104) Versus mFOLFOX6 Alone in Locally Advanced Colorectal Cancer: a Randomized Control Phase II Study (OPTICAL-2)
Latest Information Update: 05 Jan 2024
At a glance
- Drugs Cadonilimab (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary)
- Indications Adenocarcinoma; Colorectal cancer
- Focus Therapeutic Use
- Acronyms OPTICAL-2
Most Recent Events
- 26 Dec 2023 Number of treatment arms are increased from 2 to 3 by the addition of Active Comparator: mFOLFOXIRI arm.
- 26 Dec 2023 Planned number of patients changed from 82 to 143.
- 26 Dec 2023 Status changed from not yet recruiting to recruiting.