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A Non-randomized, Open-label, Fixed-sequence Phase I Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD5305 in Patients With Advanced Solid Malignancies

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Trial Profile

A Non-randomized, Open-label, Fixed-sequence Phase I Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD5305 in Patients With Advanced Solid Malignancies

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 19 Jun 2024

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At a glance

  • Drugs Itraconazole (Primary) ; Saruparib (Primary)
  • Indications Solid tumours
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

Most Recent Events

  • 17 Jun 2024 Status changed from active, no longer recruiting to completed.
  • 17 Aug 2023 Planned End Date changed from 27 Jul 2023 to 25 Apr 2024.
  • 17 Aug 2023 Status changed from recruiting to active, no longer recruiting.

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