Trial Profile

A Phase 1/2 Clinical Study to Evaluate the Safety and Efficacy of Single Dose Intravenous Infusion of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 07 Mar 2024

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At a glance

12 Dec 2023 Results of pooled analysis (NCT05577312, NCT04211480 and NCT04205435) assessing adverse events, neutrophil and platelet engraftment, Efficacy assessments included proportion of transfusion-independent (TI) subjects, levels of total hemoglobin and HbF, and proportion of red blood cells expressing HbF in peripheral blood, were presented at the 65th American Society of Hematology Annual Meeting and Exposition.
07 Nov 2022 Status changed from not yet recruiting to recruiting.
17 Oct 2022 New trial record

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