A Phase 0/2 Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma
Latest Information Update: 24 Mar 2026
At a glance
- Drugs Safusidenib (Primary)
- Indications Glioma
- Focus Adverse reactions; Pharmacokinetics
Most Recent Events
- 18 Mar 2026 Status changed from recruiting to completed.
- 01 Oct 2025 Primary endpoint (Phase 0: Feasibility of Phase 0 study in patient population) has been met, according to results published in the Nature Medicine.
- 01 Oct 2025 Results (n=10, data cut-off: 8 Nov 2024) assessing endpoints from the perioperative component of the study, to assess biological effects of mIDH1 inhibition in tumor and peri-tumoral brain,including safety till a median duration of 14 months, published in the Nature Medicine