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Phase I/II randomized trial of LB-100 plus doxorubicin vs. doxorubicin alone in first line of advanced soft tissue sarcomas

Trial Profile

Phase I/II randomized trial of LB-100 plus doxorubicin vs. doxorubicin alone in first line of advanced soft tissue sarcomas

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 25 Mar 2025

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At a glance

  • Drugs Doxorubicin (Primary) ; LB 100 (Primary)
  • Indications Fibrosarcoma; Leiomyosarcoma; Malignant fibrous histiocytoma; Myxoid liposarcoma; Nerve sheath neoplasms; Soft tissue sarcoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ENHANCER

Most Recent Events

  • 19 Aug 2024 According to a Lixte Biotechnology Holdings media release, the company expect to see the data from this first phase early in 2025
  • 19 Jan 2024 Planned primary completion date changed from 8 Nov 2023 to 20 Jun 2025.
  • 07 Jun 2023 According to a Lixte Biotechnology Holdings media release, 3 sites are active in Spain now and 3 additional sites will join the Phase 1b part in the coming weeks.

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