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A Phase 3, Randomized, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination With R-CHOP Compared to R-CHOP in Subjects With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Trial Profile

A Phase 3, Randomized, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination With R-CHOP Compared to R-CHOP in Subjects With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 28 Jan 2025

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At a glance

  • Drugs Epcoritamab (Primary) ; Rituximab (Primary) ; Rituximab (Primary) ; Cyclophosphamide; Doxorubicin; Doxorubicin; Prednisolone; Prednisone; Vincristine
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms EPCORE DLBCL-2
  • Sponsors AbbVie Germany; Genmab

Most Recent Events

  • 23 Jan 2025 Status changed from recruiting to active, no longer recruiting.
  • 04 Dec 2024 Planned End Date changed from 30 Dec 2029 to 1 Dec 2029.
  • 04 Dec 2024 Planned primary completion date changed from 24 Sep 2028 to 1 Jun 2027.

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