Trial Profile

A Phase 1/2 Trial of Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation

Status: Discontinued

Phase of Trial: Phase I

Latest Information Update: 30 Apr 2025

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At a glance

Drugs Adagrasib (Primary) ; Sirolimus (Primary)
Indications Non-small cell lung cancer; Solid tumours
Focus Adverse reactions; Therapeutic Use
Acronyms KRYSTAL -19
Sponsors Mirati Therapeutics

Most Recent Events

25 Apr 2025 Status changed from active, no longer recruiting to discontinued as the Business objectives have changed
13 May 2024 Status changed from recruiting to active, no longer recruiting.
09 Aug 2023 According to Aadi Biosciences media release, first patient had been dosed in this trial

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