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A Single-arm, Multi-center, Phase Ib/II Study of Selinexor in Combination With R-CHOP Followed by Selinexor Maintenance for Untreated EBV-positive DLBCL Patients (Xplore Trial)

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Trial Profile

A Single-arm, Multi-center, Phase Ib/II Study of Selinexor in Combination With R-CHOP Followed by Selinexor Maintenance for Untreated EBV-positive DLBCL Patients (Xplore Trial)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Dec 2023

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At a glance

  • Drugs Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Prednisone (Primary) ; Rituximab (Primary) ; Selinexor (Primary) ; Vincristine (Primary)
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms Xplore Trial

Most Recent Events

  • 13 Dec 2023 Planned primary completion date changed from 31 Mar 2024 to 31 Dec 2024.
  • 19 Oct 2022 New trial record

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