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A Single-Arm, Open-Label Phase 1b Study of Hyper-CVAD + Calaspargase Pegol in Young Adults With Newly Diagnosed Acute Lymphoblastic Leukemia

Trial Profile

A Single-Arm, Open-Label Phase 1b Study of Hyper-CVAD + Calaspargase Pegol in Young Adults With Newly Diagnosed Acute Lymphoblastic Leukemia

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Jul 2024

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At a glance

  • Drugs Calaspargase pegol (Primary) ; Cyclophosphamide (Primary) ; Cytarabine (Primary) ; Dexamethasone (Primary) ; Doxorubicin (Primary) ; Mesna (Primary) ; Methotrexate (Primary) ; Rituximab (Primary) ; Vincristine (Primary)
  • Indications Acute myeloid leukaemia; Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor T-cell lymphoblastic leukaemia-lymphoma
  • Focus Therapeutic Use

Most Recent Events

  • 26 Jun 2024 Planned End Date changed from 1 Nov 2027 to 1 May 2027.
  • 26 Jun 2024 Planned primary completion date changed from 1 Nov 2024 to 1 May 2025.
  • 12 Feb 2024 Planned End Date changed from 1 Sep 2027 to 1 Nov 2027.

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